Coagulation

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News • On-demand reversibility

Anticoagulation with an ‘on/off’ switch

Researchers developed a new type of anticoagulant whose action can be rapidly stopped. This reversible activity could revolutionise the use of anticoagulants in surgery or other applications.

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News • Warfarin, personalised

AI helps dosing anticoagulation meds in heart surgery patients

Warfarin is sometimes prescribed after heart surgery, but getting the dose right requires a personalised approach for each patient. A new AI tool is designed to help with this complex task.

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News • New tool against cerebral venous sinus thrombosis

Using an ultrasound ‘vortex’ to break down blood clots

Researchers have developed a new tool and technique that uses “vortex ultrasound” – a sort of ultrasonic tornado – to break down blood clots in the brain.

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News • Protein malformation

Covid-19: immune reaction may cause amyloid generation

In patients with serious and long-term Covid-19, disturbed blood coagulation is often observed. Now, Swedish researchers found a connection between harmful amyloid production and Covid-19 symptoms.

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News • After vaccination

Covid-19: Clinicians uncover rare blood clotting syndrome

A team led by a clinical academic at University College London (UCL) has outlined the mechanism behind rare cases of blood clots and low platelets seen in patients who have had the Oxford/AstraZeneca…

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News • Anticoagulants vs coronavirus

Preventive blood thinning could reduce risk of Covid-19 death

Patients given preventive blood thinning drugs (prophylactic anticoagulants) within 24 hours of admission to hospital with Covid-19 are less likely to die compared with those who do not receive them,…

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News • Cancer research

Exploring the benefits of anticoagulants against brain metastases

Brain metastases can only develop if cancer cells first exit the fine blood vessels and enter into the brain tissue. To facilitate this step, cancer cells influence blood clotting, as scientists from the German Cancer Research Center and Heidelberg University Hospital have now been able to show in mice. The cancer cells actively promote the formation of clots, which helps them to arrest in the…

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News • Antithrombotic approach

A new way to detect blood clots

Biomedical engineering researchers at Texas A&M University designed a medical device that mimics blood vessels to design and monitor drugs for patients with clotting disorders. This approach could be especially beneficial for pediatric patients. Unlike what a biology textbook may show, blood vessels are not straight cylinders. They are tortuous, meaning they have complex curves, spirals and…

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News • Blood coagulation

Treating hemophilia with gene therapy

Within the framework of an international study, Lund University and Skåne University Hospital have started treating patients with hemophilia with gene therapy, something that began in January this year. The hope is that the new treatment will significantly simplify everyday life for those with severe hemophilia. Hemophilia is a genetic disease where the body does not produce one of the clotting…

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News • Blood thinning 2.0

Developing next generation anticoagulants

A University of Leeds spin-out company has secured £3.14m to develop a next generation drug that aims to prevent blood clots forming, without the risk of bleeding present in currently available drugs. Currently, anticoagulants have a relatively narrow margin between beneficial effects and undesirable bleeding, so new approaches are in demand. These could allow more patients that have a higher…

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News • Venous thromboembolism (VTE)

Award for new blood clot prevention technology

A partnership between the Royal Stoke University Hospital, part of the University Hospitals of North Midlands NHS Trust, and a UK industry-leading medical devices company have been rewarded for its use of an innovative bioelectronic technology to prevent life-threatening blood clots in acute stroke patients – winning in the category: Best use of technology (acute care), at the Building Better…

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News • Blood thinners

Experts' plea for anticoagulant dosage guidelines

Rutgers researchers have found a way to reduce bleeding in patients following bariatric surgery. The study, which appeared in the journal Surgery for Obesity and Related Disorders, was conducted by Luigi Brunetti and Leonid Kagan at the Rutgers Ernest Mario School of Pharmacy in collaboration with Ragui Sadek at Advanced Surgical and Bariatrics of New Jersey. More than 30 percent of adults in the…

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Sponsored • Coagulation

‘Sensational’ innovations for radio surgery

Back in 1987 Meyer-Haake GmbH introduced the first high-frequency surgical device with an output power in the megahertz range. Due to the high-frequency it was possible to conduct surgery with minimal heat development, resulting in less thermal damage and tissue shrinkage. Thus, the firm’s devices were quickly bought. For its latest models – radioSURG 2200 ‘PT’ and ‘PTA’ –…

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News • Fully automated coagulation analyzers

HORIBA Medical launches Yumizen G1500/G1550

HORIBA Medical announces that the Yumizen G1500 (open tube) and Yumizen G1550 (closed tube) are now available. These fully automated analyzers can manage the diagnostic and monitoring requirements of clinical laboratories with a mid to high workload. Expanding their field of blood-diseases expertise, directly linked to hematology, HORIBA Medical is now able to offer its customers, dedicated and…

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Sponsored • Manufacturers vs. bureaucracy

‘We will master this problem’

Manufacturers are required to prevent so-called anomalous use. This includes, for instance, the use of cuvettes that are not licensed in products like Teco’s Coatron-X. Norms and directives are the backbone of medical devices manufacture. Frequent updates keep them current, but also often create unforeseen problems, especially for smaller and medium-size companies, because the bureaucracy is…

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